%A Hosaina, habibah Wulandarena %A Siagian, Zuhendi Arifan %A ., Florenly %A Sim, Mellisa %D 2021 %T Uji Potensial Antibakteri Ekstrak Daun Salam (Syzygium Polyanthum) - Kitosan Nanopartikel 1% Terhadap Pertumbuhan Bakteri Staphylococcus Aureus %K %X Lately, There have been many studies about s alam leaf extract and chitosan nanoparticle 1% which have antibacterial potential on both gram-negative and gram-positive bacteria . R esearchers interested for mixing two of ingredients use as an alternative antibacterial that will be more effective for future. Th e aims of study to determine the antibacteria l potential s alam leaf extract - chitosan nanoparticles 1% against the growth of Staphylococcus aureus . Salam leaf extract made by maceration method and converted into 50%, 75% and 100% concentrations , mixed with c hitosan nanoparticles 1% ionic gelation method ratio 1 : 1 so there was three research groups . The antibacterial potensial tested by the disc diffusion method (Kirby-Bauer test) . Based on one way ANOVA statistical , it showed significance value of p = 0,000 (p <0.05) so that means there was differences in the average diameter of inhibit ory s alam leaf extract 50%, 75% and 100% - c hitosan nanoparticles 1% againt the growth of Staphylococcus aureus where is the results are 12.30 ± 0.2530 mm, 13.25 ± 0.3728 mm, 14.10 ± 0.1789 mm and reinforced by the Pearson correlation tes t . Thus the combination of 100% concentration salam leaf extract - c hitosan nanoparticles 1% proved to be the most potential againt Staphylococcus aureus . %U http://jurnal.pdgi.or.id/index.php/jmkg/article/view/470 %J Jurnal Material Kedokteran Gigi %0 Journal Article %R 10.32793/jmkg.v9i2.470 %P 47-56%V 9 %N 2 %@ 2302-5271 %8 2021-02-14