Denture Stomatitis with Diabetes Mellitus and Anemia: A Case Report
Abstract
Introduction: Denture stomatitis (DS) is a common problem among denture wearers. It usually appears as redness or inflammation of the oral mucosa that encounters the denture base. The causes are often not limited to one factor. Poor denture hygiene, wearing dentures continuously, and ill-fitting dentures are common triggers. However, systemic conditions such as diabetes mellitus can also play a major role by reducing the body’s ability to fight infection. Case Report: A 54-year-old woman presented to the Dental Hospital at Universitas Syiah Kuala with complaints of redness on the hard palate. She mentioned that her denture had become loose and often fell out when she talked or chewed food. Intraoral examination revealed diffuse erythematous, measuring >2 cm, red in color, number 2 (bilateral), irregular edges, located on the hard palate. Atrophic lesions, flat, measuring ±3x5cm, red in color, multiple, with diffuse borders and irregular edges, located on the dorsal surface of the tongue. Blood examination revealed elevated blood glucose and HbA1c levels, along with low hemoglobin, hematocrit, Mean Corpuscular Volume (MCV), and Mean Corpuscular Hemoglobin (MCH) values. Based on the patient’s history, clinical features, and laboratory results, the case was diagnosed as denture stomatitis type II (Newton’s classification) associated with diabetes mellitus and mild anemia. The patient was treated with Nystatin oral suspension and Chlorhexidine Gluconate 0.2%, blood glucose control and improved nutrition were emphasized to support the healing process and enhance systemic health. In addition, the patient was advised to adjust the denture. Conclusion: Management of this condition must be comprehensive, starting with proper diagnosis of the causative and risk factors, then directing treatment to the most significant factors specific to the patient.References
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Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview Mujeeb. Avicenna J Med. 2020;10(04):174-88. doi:10.4103/ajm.ajm
Sumitro, Cuan HK, Halim S. Denture stomatitis: an overview of epidemiology, etiology, and current therapeutic strategies. J Inov Pendidik Mat dan IPA. 2025;5(2):965-74.
Rani.s L, Dharman S, G.Maragathavalli. Assessment of diabetic status in denture stomatitis and angular cheilitis patients in a university hospital setting-a retrospective analysis. Int J Dent Oral Sci. 2019;2(4):36-41. doi:10.19070/2377-8075-si02-04008
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Raman N, Jain S. Oral symptoms of diabetes mellitus in complete denture wearers patients: a case control study. Int J Pharm Clin Res. 2021;13(6):393-400.
Suragimath G, SR A, Christopher V, Al E. Oral candidiasis in diabetic patients- case report with treatment. World J Pharm Res. 2016;5(3):741-46.
Ramamurthy J. Prevalence of oral mucosal lesions in patients with type ii diabetes mellitus: a retrospective analysis. World J Dent. 2023;14(8):683-87
Nicholson-Becerra CD, Orozco-Gallardo M, Cisneros-Moya A, et al. Oral candidiasis in a diabetic patient wearing bar-retained provisional overdenture: clinical case report. Reports. 2024;7(4):96. doi:10.3390/reports7040096
Abuhajar E, Ali K, Zulfiqar G, et al. Management of chronic atrophic candidiasis (denture stomatitis)—a narrative review. Int J Environ Res Public Health. 2023;20(4). doi:10.3390/ijerph20043029
Sartawi SY, Abu-Hammad S, Salim NA, Al-Omoush S. Denture stomatitis revisited: a summary of systematic reviews in the past decade and two case reports of papillary hyperplasia of unusual locations. Int J Dent. Published online 2021:1-8. doi:10.1155/2021/7338143
González-Serrano J, Serrano J, López-Pintor RM, et al. Prevalence of oral mucosal disorders in diabetes mellitus patients compared with a control group. J Diabetes Res. 2016; 1-11. doi:10.1155/2016/5048967
Djou R, Wahyuni IS. Atrophic glossitis as a clinical sign for anemia in the elderly. Dentino (JurKedGigi). 2019;IV(1):70-76.
Gopal S, Srividhya S, Sushmitha S. Oral manifestations a key in diagnosing iron deficiency anemia–a case report. J Res Med Dent Sci. 2021;9(4):438-41.
Bukhari MA, Algahtani MA, Alsuwailem FA, Alogaiel RM, et al. Epidemiology, etiology, and treatment of denture stomatitis. Int J community Med Public Heal. 2022;9(2):981-86. doi: 6040.ijcmph20220003
Eyadeh A Al, Al-Qaisi R, Rumman KA, Shibli A, Aburumman R, Aburumman R. Effect of glycemic control on candida colonization on complete denture wearers of diabetic patients. Rawal Med J. 2022;47(3):552-55.
Weerasinghe J, Weerasinghe L, Thirugnanasampanthar V, Jayasooriya P, Lombardi T. Cross-sectional study on proportions of type 2 diabetic patients presenting with oral candidal lesions. Appl Sci. 2025;15(10):1-12. doi:10.3390/app15105539
Banday MZ, Sameer AS, Nissar S. Pathophysiology of diabetes: An overview Mujeeb. Avicenna J Med. 2020;10(04):174-88. doi:10.4103/ajm.ajm
Sumitro, Cuan HK, Halim S. Denture stomatitis: an overview of epidemiology, etiology, and current therapeutic strategies. J Inov Pendidik Mat dan IPA. 2025;5(2):965-74.
Rani.s L, Dharman S, G.Maragathavalli. Assessment of diabetic status in denture stomatitis and angular cheilitis patients in a university hospital setting-a retrospective analysis. Int J Dent Oral Sci. 2019;2(4):36-41. doi:10.19070/2377-8075-si02-04008
Rodríguez-Archilla A, Piedra-Rosales C. Candida species oral detection and infection in patients with diabetes mellitus: a meta-analysis. Iberoam J Med. 2021;3(2):115-21. doi:10.53986/ibjm.2021.0020
Raman N, Jain S. Oral symptoms of diabetes mellitus in complete denture wearers patients: a case control study. Int J Pharm Clin Res. 2021;13(6):393-400.
Suragimath G, SR A, Christopher V, Al E. Oral candidiasis in diabetic patients- case report with treatment. World J Pharm Res. 2016;5(3):741-46.
Ramamurthy J. Prevalence of oral mucosal lesions in patients with type ii diabetes mellitus: a retrospective analysis. World J Dent. 2023;14(8):683-87
Published
2025-10-31
How to Cite
RAMBE, Sarinah et al.
Denture Stomatitis with Diabetes Mellitus and Anemia: A Case Report.
Journal of Indonesian Dental Association, [S.l.], v. 8, n. 2, p. 98-101, oct. 2025.
ISSN 2621-6175.
Available at: <http://jurnal.pdgi.or.id/index.php/jida/article/view/1465>. Date accessed: 27 nov. 2025.
doi: https://doi.org/10.32793/jida.v8i2.1465.
Section
Case Report





