Oral Manifestation Impact of Moebius Syndrome towards Oral Health-related Quality of Life
A Case Report
Abstract
Background Moebius syndrome is a rare disease characterized by unilateral or bilateral congenital facial palsy and disability of ocular abduction, and may also involve other cranial nerves palsy. Moebius syndrome is also known to have many orofacial anomalies, such as cleft palate, micrognathia, gothic palate, tongue weakness, tongue atrophy, microstomia, and open bite. Objective This case report discusses about Moebius syndrome and denture stomatitis and its management considerations. Case Report A 22-year-old female patient came to the oral medicine clinic of Dental Hospital Universitas Indonesia, referred from prosthodontist with working diagnosis of denture stomatitis. From objective examination, we found microstomia, tongue defect with movement limitations, and gothic palate with erythematous patch on the denture-bearing area. The patient denied any relevant medical history. However, she admitted that she was not satisfied with her oral condition. Based on the signs presented, we performed further examination and found impaired ocular abduction. Furthermore, we gave her Oral Health Impact Profile (OHIP)-14 questionnaire to assess her oral health-related quality of life. These examinations resulted in the diagnosis of Moebius syndrome with denture stomatitis and poor oral health-related quality of life. We planned a full mouth rehabilitation consisting of denture stomatitis healing, improving of oral hygiene, root canal therapy, and renewed the denture. Conclusion Dentists must be aware of patient’s oral condition but also the association between oral cavity and general health. By having thorough examination, we can reach definitive diagnosis and make the appropriate treatment plan which in turn improve the oral health-related quality of life of the patient.References
1. De Stefani E, Nicolini Y, Belluardo M, Ferrari PF. Congenital facial palsy and emotion processing: The case of Moebius syndrome. Genes Brain Behav. 2019;18(1):1-15.
2. Picciolini O, Porro M, Cattaneo E, et al. Moebius syndrome: clinical features, diagnosis, management and early intervention. Ital J Pediatr. 2016;42(1):56.
3. De Serpa Pinto MVX, De Magalhães MHCG, Nunes FD. Moebius syndrome with oral involvement. Int J Paediatr Dent. 2002;12(6):446-449.
4. Ortega A de OL, Marques-Dias MJ, Santos MTBR dos, Castro T, Gallottini M. Oral motor assessment in individuals with Moebius syndrome. J Oral Pathol Med. 2014;43(2):157-161.
5. Mahrous A, Thalji G. Prosthodontic Management of a Patient with Moebius Syndrome: A Clinical Report. J Prosthodont. 2018;27(3):299-305.
6. MacKinnon S, Oystreck DT, Andrews C, Chan W-M, Hunter DG, Engle EC. Diagnostic distinctions and genetic analysis of patients diagnosed with Moebius syndrome. Ophthalmology. 2014;121(7):1461-1468.
7. Bell C, Nevitt S, McKay VH, Fattah AY. Will the real Moebius syndrome please stand up? A systematic review of the literature and statistical cluster analysis of clinical features. Am J Med Genet A. 2019;179(2):257-265.
8. Broussard AB, Borazjani JG. The faces of Moebius syndrome: Recognition and anticipatory guidance. MCN Am J Matern Child Nurs. 2008;33(5):272-278.
9. Patil S, Rao RS, Majumdar B, Anil S. Clinical appearance of oral candida infection and therapeutic strategies. Front Microbiol. 2015;6:1391.
10. A proposal for reclassification of oral candidosis. Oral Surg Oral Med Oral Pathol. 1997;(2):111-112.
11. Garcia-Cuesta C, Sarrion-Pérez MG, Bagán J V. Current treatment of oral candidiasis: A literature review. J Clin Exp Dent. 2014;6(5):e576-e582.
12. Silveira MF, Pinho L de, Brito MFSF. Validity and Reliability of the Oral Health Impact Profile Instrument (OHIP-14) in Adolescents. Paid (Ribeirão Preto). 2019;29.
13. Husain FA, Tatengkeng F. Oral Health-Related Quality of Life Appraised by OHIP-14 Between Urban and Rural Areas in Kutai Kartanegara Regency, Indonesia: Pilot Pathfinder Survey. Open Dent J. 2017;11(1):557-564.
14. Ratnawidya W, Rahmayanti F, Soegiyanto AI, Mandasari M, Wardhany II. Indonesian short version of the Oral Health Impact Profile (OHIP-14). J Int Dent. 2018;11(3):1065-1071.
15. Bogart KR, Matsumoto D. Living with Moebius syndrome: Adjustment, social competence, and satisfaction with life. Cleft Palate Craniofac J. 2010;47(2):134-142.
16. Bogart KR, Tickle-Degnen L, Joffe MS. Social interaction experiences of adults with Moebius Syndrome: A focus group. J Heal Psychol. 2012;17(8):1212-1222.
17. Martins Mussi MC, Moffa E, Castro T, et al. Salivary parameters and oral health in the Moebius syndrome. Spec Care Dent. 2016;36(5):265-270.
2. Picciolini O, Porro M, Cattaneo E, et al. Moebius syndrome: clinical features, diagnosis, management and early intervention. Ital J Pediatr. 2016;42(1):56.
3. De Serpa Pinto MVX, De Magalhães MHCG, Nunes FD. Moebius syndrome with oral involvement. Int J Paediatr Dent. 2002;12(6):446-449.
4. Ortega A de OL, Marques-Dias MJ, Santos MTBR dos, Castro T, Gallottini M. Oral motor assessment in individuals with Moebius syndrome. J Oral Pathol Med. 2014;43(2):157-161.
5. Mahrous A, Thalji G. Prosthodontic Management of a Patient with Moebius Syndrome: A Clinical Report. J Prosthodont. 2018;27(3):299-305.
6. MacKinnon S, Oystreck DT, Andrews C, Chan W-M, Hunter DG, Engle EC. Diagnostic distinctions and genetic analysis of patients diagnosed with Moebius syndrome. Ophthalmology. 2014;121(7):1461-1468.
7. Bell C, Nevitt S, McKay VH, Fattah AY. Will the real Moebius syndrome please stand up? A systematic review of the literature and statistical cluster analysis of clinical features. Am J Med Genet A. 2019;179(2):257-265.
8. Broussard AB, Borazjani JG. The faces of Moebius syndrome: Recognition and anticipatory guidance. MCN Am J Matern Child Nurs. 2008;33(5):272-278.
9. Patil S, Rao RS, Majumdar B, Anil S. Clinical appearance of oral candida infection and therapeutic strategies. Front Microbiol. 2015;6:1391.
10. A proposal for reclassification of oral candidosis. Oral Surg Oral Med Oral Pathol. 1997;(2):111-112.
11. Garcia-Cuesta C, Sarrion-Pérez MG, Bagán J V. Current treatment of oral candidiasis: A literature review. J Clin Exp Dent. 2014;6(5):e576-e582.
12. Silveira MF, Pinho L de, Brito MFSF. Validity and Reliability of the Oral Health Impact Profile Instrument (OHIP-14) in Adolescents. Paid (Ribeirão Preto). 2019;29.
13. Husain FA, Tatengkeng F. Oral Health-Related Quality of Life Appraised by OHIP-14 Between Urban and Rural Areas in Kutai Kartanegara Regency, Indonesia: Pilot Pathfinder Survey. Open Dent J. 2017;11(1):557-564.
14. Ratnawidya W, Rahmayanti F, Soegiyanto AI, Mandasari M, Wardhany II. Indonesian short version of the Oral Health Impact Profile (OHIP-14). J Int Dent. 2018;11(3):1065-1071.
15. Bogart KR, Matsumoto D. Living with Moebius syndrome: Adjustment, social competence, and satisfaction with life. Cleft Palate Craniofac J. 2010;47(2):134-142.
16. Bogart KR, Tickle-Degnen L, Joffe MS. Social interaction experiences of adults with Moebius Syndrome: A focus group. J Heal Psychol. 2012;17(8):1212-1222.
17. Martins Mussi MC, Moffa E, Castro T, et al. Salivary parameters and oral health in the Moebius syndrome. Spec Care Dent. 2016;36(5):265-270.
Published
2024-11-13
How to Cite
PARAMITA, Felicia; SASANTI, Harum; PRADONO, Siti Aliyah.
Oral Manifestation Impact of Moebius Syndrome towards Oral Health-related Quality of Life.
Journal of Indonesian Oral Medicine Society, [S.l.], v. 2, n. 2, p. 1-6, nov. 2024.
ISSN 3026-6688.
Available at: <http://jurnal.pdgi.or.id/index.php/jioms/article/view/1244>. Date accessed: 30 dec. 2024.
doi: https://doi.org/10.32793/jioms.v2i2.1244.
Section
Case Reports
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
