The Correlation between Subjective Complaint of Dry Mouth, Unstimulated Salivary Flow Rate, and Oral Mucosal Dryness in Patients with Sjogren’s Syndrome
Abstract
Background Sjogren’s syndrome is an autoimmune disease that is characterized by the classic symptoms of dry mouth, dry eyes, and arthritis. The most common symptom is called sicca symptoms which consist of keratoconjunctivitis sicca and hyposalivation and xerostomia. Many papers use the term xerostomia and hyposalivation interchangeably. However, these two terms define different conditions. Xerostomia is used to describe the subjective complaint of dry mouth whereas hyposalivation is objectively measured. Objective To examine the correlation between xerostomia, unstimulated salivary flow rate, and oral mucosal dryness in patients with Sjogren’s syndrome. Results Summated xerostomia inventory Indonesian version (SXI-ID_and clinical oral dryness score (CODS) is negatively correlated with unstimulated salivary flow rate. Whereas SXI-ID is positively correlated with CODS. Conclusion Xerostomia is assessed using SXI-ID which is not always followed by hyposalivation. The hyposalivation affects the wettability of oral mucosa, as it negatively correlated with oral mucosa dryness. Further study is needed to investigate the detailed correlation between xerostomia and hyposalivation, and factors affecting them.References
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2. Vivino FB. Sjogren’s syndrome: Clinical aspects. Clin Immunol. 2017;182:48-54.
3. Zandonella Callegher S, Giovannini I, Zenz S, et al. Sjögren syndrome: looking forward to the future. Ther Adv Musculoskelet Dis. 2022;14:1759720X2211002.
4. Baer AN, Walitt B. Sjögren Syndrome and Other Causes of Sicca in Older Adults. Clin Geriatr Med. 2017;33(1):87-103.
5. Hopcraft M, Tan C. Xerostomia: an update for clinicians: Xerostomia: an update for clinicians. Aust Dent J. 2010;55(3):238-244.
6. Wimardhani YS, Rahmayanti F, Maharani DA, Mayanti W, Thomson WM. The validity and reliability of the Indonesian version of the Summated Xerostomia Inventory. Gerodontology. 2021;38(1):82-86.
7. Jager DHJ, Bots CP, Forouzanfar T, Brand HS. Clinical oral dryness score: evaluation of a new screening method for oral dryness. Odontology. 2018;106(4):439-444.
8. Tan Z, Wang L, Li X. Composition and regulation of the immune microenvironment of salivary gland in Sjögren’s syndrome. Front Immunol. 2022;13:967304.
9. Negrini S, Emmi G, Greco M, et al. Sjögren’s syndrome: a systemic autoimmune disease. Clin Exp Med. 2022;22(1):9-25.
10. Ahmad M, Bhayat A, Zafar M, Al-Samadani K. The Impact of hyposalivation on quality of life (QoL) and oral health in the aging population of Al Madinah Al Munawarrah. Int J Environ Res Public Health. 2017;14(4):445.
11. Sarkar A, Andablo-Reyes E, Bryant M, Dowson D, Neville A. Lubrication of soft oral surfaces. Curr Opin Colloid Interface Sci. 2019;39:61-75.
12. Hijjaw O, Alawneh M, Ojjoh K, et al. Correlation between xerostomia index, clinical oral dryness scale, and ESSPRI with different hyposalivation tests. Open Access Rheumatol Res Rev. 2019;Volume 11:11-18.
13. Won SH, Kho HS, Kim YK, Chung SC, Lee SW. Analysis of residual saliva and minor salivary gland secretions. Arch Oral Biol. 2001;46(7):619-624.
Published
2024-11-13
How to Cite
PARAMITA, Felicia; AMANI, Chininta Oktora; TRI WULANDARI, Endah Ayu.
The Correlation between Subjective Complaint of Dry Mouth, Unstimulated Salivary Flow Rate, and Oral Mucosal Dryness in Patients with Sjogren’s Syndrome.
Journal of Indonesian Oral Medicine Society, [S.l.], v. 2, n. 2, p. 27-31, nov. 2024.
ISSN 3026-6688.
Available at: <http://jurnal.pdgi.or.id/index.php/jioms/article/view/1245>. Date accessed: 30 dec. 2024.
doi: https://doi.org/10.32793/jioms.v2i2.1245.
Section
Original Research
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
