Interplay of Stress and Gastroesophageal Reflux Disease

A Case Study of Recurrent Aphthous Stomatitis

Abstract

Background Recurrent Aphthous Stomatitis (RAS) is a common and painful oral mucosal condition characterized by recurrent ulcerations. While its exact aetiology remains multifactorial and not fully understood, predisposing factors such as psychological stress and systemic conditions like Gastroesophageal Reflux Disease (GERD) have been implicated in its recurrence and severity. This case report explores the clinical course and multidisciplinary management of RAS in a patient with underlying GERD and elevated stress levels. Case report A 24-year-old female presented with recurrent, painful oral ulcers, primarily occurring before menstruation. The patient also had a medical history of GERD and reported high stress levels due to a demanding lifestyle. Clinical examination revealed minor aphthous ulcers on the buccal mucosa, while laboratory findings were within normal references. Management involved a comprehensive therapeutic plan that included topical anti-inflammatory and antiseptic agents, multivitamins, improved oral hygiene practices, dietary modification, and stress reduction through regular exercise. Significant clinical improvement was observed following treatment. Conclusion: This case highlights the importance of a holistic, patient-centred approach in managing RAS, especially when systemic conditions such as GERD and behavioural factors like stress are involved. Long-term monitoring and interprofessional collaboration are essential for sustained remission and improved quality of life.