Exploring the radiographic distinctions between ewing's sarcoma and malignant and fibrous ameloblastoma: a clinical case report and review
Abstract
Objectives: Ewing's sarcoma and fibrous ameloblastoma are distinct entities that can present similarly in imaging studies, posing challenges in accurate diagnosis. This report aims to elucidate the radiographic features that differentiate these two lesions.Case Report: The first case was a 7-year-old boy who came to the radiology installation accompanied by his mother for a panoramic radiography examination. The patient complained of swelling on both sides of the lower jaw for 1.8 years. The second case was an 8-year-old boy who came with a referral for a panoramic radiography examination due to swelling on the left side of the lower jaw for 6 months. The first case was radiographically determined as Differential Radiodiagnosis Ewing sarcoma and malignant ameloblastoma, and the second case was radiographically determined as fibrous ameloblastoma with differential Radiodiagnosis malignant ameloblastoma. The differential diagnosis between Ewing's sarcoma and fibrous ameloblastoma is critical due to their distinct treatment protocols and prognoses. This case underscores the importance of comprehensive imaging evaluation and correlating clinical findings to achieve an accurate diagnosis.
Conclusion: This case report contributes to the understanding of radiographic distinctions among Ewing's sarcoma, fibrous ameloblastoma, and malignant ameloblastoma. Enhanced awareness of these differences may improve diagnostic accuracy and inform treatment strategies. This abstract provides a succinct overview of the case report, highlighting essential elements such as background information, case details, discussion points, and conclusions relevant to radiographic distinctions between the two conditions.
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4. Abir B, Abouchadi A, Tourabi K, Lakouichmi M. Ameloblastic carcinoma of the mandible: A case report and review of the literature. Medecine Buccale Chirurgie Buccale. EDP Sciences; 2017; 23 (2) : 95–98.
5. Gupta N, Anjum R, Lone P. Ameloblastoma of the Mandible: A Case Report with Review of Literature. Int J Head Neck Surg. 2012;3(1):56–58.
6. Masthan KMK, Anitha N, Krupaa J, Manikkam S. Ameloblastoma. Journal of Pharmacy and Bioallied Sciences. Wolters Kluwer Medknow Publications. 2015;7(1): 167–170.
7. Gumgum S, Hosgoren B. Clinical and Radiologic Behaviour of Ameloblastoma in 4 Cases. J Can Dent Assoc 2005;71(7):481– 484.
8. Balkaya E, Bozkurt C, Aksu AE, Özmen S, Özdemir Sİ, Şahin G. Ewing`s sarcoma of the mandible misdiagnosed as periodontal inflammation: Report of three cases. Turk J Pediatr. 2017;59(6):704–707.
9. Toomey EC, Schiffman JD, Lessnick SL. Recent advances in the molecular pathogenesis of Ewing’s sarcoma. Oncogene. 2010;29(32):4504–4516.
10. Franzetti GA, Laud-Duval K, Van Der Ent W, Brisac A, Irondelle M, Aubert S, et al. Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells. Oncogene. 2017;36(25):3505–3514.
11. Marco et al. Ewing’s sarcoma of the mandible in a young child. Braz Dent Journal. 2010;21(1):74–79
12. Sarifah N, Firman RN, Pramanik F, Epsilawati L. Radiographic Features Of Internal Structure In Jaw Lesions. Dentino Jurnal Kedokteran Gigi. 2019;4(1):94-100
13. KAYA S, KOÇ A, GÖYA C. Ewing Sarcoma of The Mandibular Ramus: Case Report. Van Sağlık Bilimleri Dergisi. 2023;16(2):202–206.
14. Kudva A, Kumar M, Nayak D, Sankaran M. Ewinga’ s sarcoma of the mandibular condyle in a young adult: A rare case report. Journal of Oral Medicine and Oral Surgery. 2022;28(2): 1-3.
15. White SCPMJ. Oral Radiology Principles and Interpretation. Amsterdam : Elsevier Mosby. 2014;7:441-443
16. Cho BH, Jung YH, Hwang JJ. Ameloblastic carcinoma of the mandible: A case report. Imaging Sci Dent. 2020;50(4):359–363.
17. Sharma Lamichhane N, Liu Q, Sun H, Zhang W. A case report on desmoplastic ameloblastoma of anterior mandible. BMC Res Notes. 2016;9(171): 1-7.
18. Sheikh S, Pallagatti S, Singla I, Kalucha A. Desmoplastic Ameloblastoma: A Case Report. J Dent Res Dent Clin Dent Prospects. india; 2011;5(1) : 27-32.
19. Desai P, Khorate M, Figueiredo N. Desmoplastic ameloblastoma of the mandible: A rare case report. Journal of Indian Academy of Oral Medicine and Radiology. 2020;32(1):81–85.
20. Brown NA, Betz BL. Ameloblastoma: A Review of Recent Molecular Pathogenetic Discoveries. Biomark Cancer. 2015;7(S2):19-24.
21. Bansal A, Bhatnagar A, Saxena S. Metastasizing granular cell ameloblastoma. Journal of Oral and Maxillofacial Pathology. 2012;16(1):122–124.
22. Ghai S. Ameloblastoma: An Updated Narrative Review of an Enigmatic Tumor. Cureus. 2022;14(8) :1–9.
Published
2025-12-31
How to Cite
JAMIL, Nur Aini; EPSILAWATI, Lusi; LITA, Yurika Ambar.
Exploring the radiographic distinctions between ewing's sarcoma and malignant and fibrous ameloblastoma: a clinical case report and review.
Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI), [S.l.], v. 9, n. 3, p. 171-177, dec. 2025.
ISSN 2686-1321.
Available at: <http://jurnal.pdgi.or.id/index.php/jrdi/article/view/1355>. Date accessed: 29 jan. 2026.
doi: https://doi.org/10.32793/jrdi.v9i3.1355.
Section
Case Report
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
