Characteristics of root resorption in mandibular ameloblastoma using digital radiography
DOI:
https://doi.org/10.32793/jrdi.v10i1.1500Keywords:
Ameloblastoma, digital radiography, root resorptionAbstract
Objectives: This study aims to provide insights into the characteristics of root resorption associated with ameloblastoma as detected on digital radiography.
Review: Root resorption is a pathological process marked by the progressive loss of the root structure, which may result from bacterial infection, traumatic injury, or chemical irritation. Ameloblastoma frequently exhibits distinctive patterns of root resorption, often presenting as blunted or sharply demarcated margins on digital radiographs.
Conclusion: Ameloblastoma is known for its high recurrence rate, necessitating comprehensive surgical excision to minimize the likelihood of recurrence. Surgical management often includes the removal of the affected teeth along with the tumor. These treatment decisions are generally guided by histopathological confirmation through incisional biopsy, as several lesions can mimic ameloblastoma despite characteristic radiographic findings such as root resorption.
References
1. Cardoso LB, Lopes IA, Ikuta CRS, Capelozza ALA. Study Between PanoramicRadiography and Cone Beam-Computed Tomography in the Diagnosis of Ameloblastoma, Odontogenic Keratocyst, and Dentigerous Cyst. J Craniofac Surg. 2020;31(6):1747–52.
2. To KW, Shi AH, Teh LY, Lee AMH. External root resorption in common odontogenic cysts and ameloblastomas of the jaw: A retrospective radiographic study in an Asian population. Oral Surg. 2021;14(4):335–41.
3. Liu Z, Liu J, Zhou Z, Zhang Q, Wu H, Zhai G, et al. Differential diagnosis of ameloblastoma and odontogenic keratocyst by machine learning of panoramic radiographs. Int J Comput Assist Radiol Surg [Internet]. 2021;16(3):415–22. Available from: https://doi.org/10.1007/s11548-021-02309-0
4. Lin S, Marvidou AM, Novak R, Moreinos D, Abbott PV, Rotstein I. Pathogenesis of non-infection related inflammatory root resorption in permanent teeth: A narrative review. Int Endod J. 2023;56(12):1432–45.
5. Feranasari AAIA, Epsilawati L, Pramanik F. Laporan Kasus Fitur Radiografis Ameloblastoma pada CBCT dan Panoramik. J Kedokt Gigi Univ Padjadjaran. 2020;32(1):47–51.
6. Saifuddin SD, Pramanik F, Firman RN. Analisis ameloblastoma unilokuler menggunakan radiograf cone beam computed tomography (CBCT) 3D sebagai penunjang diagnosis. J Radiol Dentomaksilofasial Indones. 2020;3(3):33.
7. Merbold LM, Smit CS, Fox JK, Uys AU. The radiologic progression of ameloblastomas. South African J Radiol. 2023;27(1):1–8.
8. Rahmel S, Schulze RKW. Accuracy in Detecting Artificial Root Resorption in Panoramic Radiography versus Tomosynthetic Panoramic Radiographs. J Endod [Internet]. 2019;45(5):634-639.e2. https://doi.org/10.1016/j.joen.2019.01.009
9. Ghai S. Ameloblastoma: An updated narrative review of an enigmatic tumor. Cureus. 2022;14(8):e27734.
10. Himammi AN, Hartomo BT. Interpretation of multilocular ameloblastoma and associated radiographic features. J Radiol Dentomaksilofasial Indones. 2021;5(1):40–43.
11. Beder R, Ibrahim M. Minimally invasive approach in the treatment of ameloblastoma in an adolescent: 3-year follow-up. Tanta Dent J. 2022;19(4):264.
12. Omami G. Honeycomb Jaw Lesion: Ameloblastoma. Ear, Nose Throat J. 2021;100(7):483–4.
13. Sargolzaei S, Atarbashi-Moghadam S, Roohi A. Mandibular Mural Ameloblastoma with Unusual Histopathologic Features: a Rare Challenging Case. J Dent (Shiraz, Iran). 2019;20(4):304–7.
14. Kakuguchi W, Ohiro Y, Nakazawa S, Naito R, Moritani Y, Nakamichi Y, et al. Application of the dredging method in a case of recurrent ameloblastoma that had spread over a large region of the mandible. J Oral Maxillofac Surgery, Med Pathol. 2020;32(1):44–8. https://doi.org/10.1016/j.ajoms.2019.09.006
15. Cadavid AMH, Araujo JP, Coutinho-Camillo CM, Bologna S, Junior CAL, Lourenço SV. Ameloblastomas: current aspects of the new WHO classification in an analysis of 136 cases. Surg Exp Pathol. 2019;2(1):4–9.
16. Bwambale P, Yahaya JJ, Owor G, Wabinga H. Histopathological patterns and biological characteristics of ameloblastoma: A retrospective cross-sectional study. J Taibah Univ Med Sci. 2022;17(1):96–104. https://doi.org/10.1016/j.jtumed.2021.09.007
17. Hu YJ, Cao R, Wang ZH, Hong WS, Zheng CY. Reconstruction of deep circumflex iliac artery free flap for multiple recurrent ameloblastoma in mandible. J Craniofac Surg. 2019;30(2):557–62.
18. Kaneko N, Sameshima J, Kawano S, Chikui T, Mitsuyasu T, Chen H, et al. Comparison of computed tomography findings between odontogenic keratocyst and ameloblastoma in the mandible: Criteria for differential diagnosis. J Oral Maxillofac Surgery, Med Pathol. 2023;35(1):15–22. https://doi.org/10.1016/j.ajoms.2022.07.016
19. Jackson J, Halim J, Anggraeni R, Sandra F. Bone Resorption in Ameloblastoma and Its Underlying Mechanism. Indones J Cancer Chemoprevention. 2021;12(1):57.
20. Ragunathan YT, Kumar SK, Janardhanam D, Ravi A, Santhanam V, Ramdas MN. Prevalence and Epidemiological Profile of Ameloblastoma in India: A Systematic Review and Meta-Analyses. Asian Pacific J Cancer Prev. 2022;23(11):3601–10.
21. Hendra FN, Van Cann EM, Helder MN, Ruslin M, de Visscher JG, Forouzanfar T, et al. Global incidence and profile of ameloblastoma: A systematic review and meta-analysis. Oral Dis. 2020;26(1):12–21.
22. Hasegawa T, Fukumoto C, Kamimura R, Tsubura Y, Yagisawa S, Izumi S, et al. A case of mandibular bone metastasis of ameloblastoma from the opposite side of the mandible: Immunohistochemical and genetic analyses of clonality. J Oral Maxillofac Surgery, Med Pathol. 2023;35(6):583–9. https://doi.org/10.1016/j.ajoms.2023.03.016
23. Peter J, Emmatty TB, Jose B, Methippara JJ, Sebastian R, Vasu S. Unicystic Ameloblastoma Associated with Primary Mandibular Second Molar: A Case Report. Int J Clin Pediatr Dent. 2023;16(S3):S335–8.
24. Schoinohoriti O, Tsami C, Karathanasi V, Kolomvos N. Mixed-Pattern Ameloblastoma of the Anterior Mandible: A Rare Histopathological Presentation at an Infrequent Location. Cureus. 2023;15(8):6–10.
25. Jehan R, Shoaib M, Afzal J, Ali M, Noor A, Jamil M, et al. Radiographic Appearance and Root Resorption Caused by Ameloblastoma in pts attending Teaching Institute of Dentistry. Pakistan J Med Heal Sci. 2023;17(2):69–72.
26. Omami G, Adel M. Width-to-length ratio comparison between ameloblastomas and odontogenic keratocysts in the body of the mandible: A preliminary study. Imaging Sci Dent. 2020;50(4):319–22.
27. Ghosh A, Lakshmanan M, Manchanda S, Bhalla AS, Kumar P, Bhutia O, et al. Contrast-enhanced multidetector computed tomography features and histogram analysis can differentiate ameloblastomas from central giant cell granulomas. World J Radiol. 2022;14(9):329–41.
28. Bispo MS, de Queiroz Pierre MLG, Apolinário AL, dos Santos JN, Junior BC, Neves FS, et al. Computer tomographic differential diagnosis of ameloblastoma and odontogenic keratocyst: Classification using a convolutional neural network. Dentomaxillofacial Radiol. 2021;50(7):1–8.
29. Nariai Y, Yanai C, Iwahashi T, Kanno T. Clinical features of giant hybrid ameloblastoma of the mandible: A case report with long-term observation of natural growth before treatment. Oral Maxillofac Surg Cases. 2019;5(3):100116. https://doi.org/10.1016/j.omsc.2019.100116
30. Luis Sebastián Pinos Pinos, Jorge Antonio Reinoso Ortiz, María Fernanda Torres Calle, Fernando Mauricio Villalta Mendoza. Unicystic ameloblastoma: A literature review. World J Adv Res Rev. 2021;10(3):095–103.
31. Urechescu H, Banu A, Baderca F, Closca RM, Ilas-Tat MB, Urtila F, et al. Ameloblastoma of the Mandible in a 16-Year-Old Female—Case Report. Med. 2024;60(1):1–8.
32. Shi HA, Ng CWB, Kwa CT, Sim QXC. Ameloblastoma: A succinct review of the classification, genetic understanding, and novel molecular targeted therapies. Surgeon. 2021;19(4):238–43. https://doi.org/10.1016/j.surge.2020.06.009
33. Goh YC, Siriwardena BSMS, Tilakaratne WM. Association of clinicopathological factors and treatment modalities in the recurrence of ameloblastoma: Analysis of 624 cases. J Oral Pathol Med. 2021;50(9):927–36.
34. Ghai S. Ameloblastoma: An Updated Narrative Review of an Enigmatic Tumor. Cureus. 2022;14(8):1–9.
35. Elmrini S, Raiteb M, Bahaha Razem, Hassani F, Zahra A, Slimani F. Ameloblastoma giant: Diagnosis, treatment, and reconstruction: A case report. Ann Med Surg. 2021;68
36. Bi L, Wei D, Hong D, Wang J, Qian K, Wang H, et al. A retrospective study of 158 cases on the risk factors for recurrence in ameloblastoma. Int J Med Sci. 2021;18(14):3326–32.
37. Ki? Hc, Co?gunarslan A, Cancer Em, Etöz M, Deniz K. Management of Ameloblastoma with Different Imaging Modalities. Turkiye Klin J Case Reports. 2020;28(3):145–55.
38. Martins GG, Oliveira IA, Consolaro A. The mechanism: how dental resorptions occur in ameloblastoma. Dental Press J Orthod. 2019 Sep 5;24(4):21-32. doi: 10.1590/2177-6709.24.4.021-032.oin. PMID: 31508703; PMCID: PMC6733230.
39. More C, Tailor M, Patel HJ, Asrani M, Thakkar K, Adalja C. Radiographic analysis of ameloblastoma: A retrospective study. J Clin Diagn Res. 2012;23(5):C05–C08.
40. Jehan R, Mujtaba H, Noor N, Shoaib M, Noor A, Afzal J, et al. Root resorption in ameloblastoma: a radiographic analysis of 35 cases. Pak J Med Health Sci. 2023;17(2):69–72.
41. Mandlik R, Parihar A, Reddy P, Singh R, Yadav N, Sharma AD. Unveiling radiographic features and radio-pathological correlations of ameloblastoma: A retrospective study. Arch Med Health Sci. 2025;(3):370–375. doi:10.4103/amhs.amhs_131.
42. Garg M, Prakash SMR, Wadhwan V, Nagaraju K, Malik S. Clinico-radiological and Histopathological Correlation of 56 Cases of Ameloblastoma : A 10-Year Retrospective Analysis in North Indian Population. 2017;2(2):2015–8.
43. Patel S, Saberi N, Pimental T, Teng PH. Present status and future directions: Root resorption. Int Endod J. 2022;55(S4):892–921.
44. Siddique AR, Motwani MB, Bankar NJ. Assessment of Digital Intraoral Periapical Radiograph for the Detection of Apical Root Resorption in Inflammatory Periapical Pathologies: A Radiovisiography Study. Cureus. 2023;15(9):2–7.
45. Heboyan A, Avetisyan A, Karobari MI, Marya A, Khurshid Z, Rokaya D, et al. Tooth root resorption: A review. Sci Prog. 2022;105(3):1–29.
46. Abbott P V., Lin S. Tooth resorption—Part 2: A clinical classification. Dentraumatol. 2022;38(4):267–85.
47. Martins GG, de Oliveira IA, Consolaro A. The mechanism: How dental resorptions occur in ameloblastoma. Dental Press J Orthod. 2019;24(4):21–32.
48. Putra PJ, Hartoyo HM, Sim M. Odontogenic Keratocyst finding with Cone Beam Computed Tomography (CBCT): a case report. J Radiol Dentomaksilofasial Indones. 2021;5(2):60.
49. Chai ZK, Mao L, Chen H, Sun TG, Shen XM, Liu J, et al. Improved diagnostic accuracy of ameloblastoma and odontogenic keratocyst on cone-beam CT by artificial intelligence. Front Oncol. 2022;12:793417. doi:10.3389/fonc.2021.793417
50. Ranchod S, Titinchi F, Behardien N, Morkel J. Ameloblastoma of the mandible: Analysis of radiographic and histopathological features. J Oral Med Oral Surg. 2021;27(1):1–8.
51. Mariz BA, Andrade BA, Agostini M, Almeida OP, Romañach MJ, Jorge J, et al. Radiographic estimation of the growth rate of initially underdiagnosed ameloblastomas. Med Oral Patol Oral Cir Bucal. 2019;24(4):e468–e472. doi:10.4317/medoral.
52. Galler KM, Grätz EM, Widbiller M, Buchalla W, Knüttel H. Pathophysiological mechanisms of root resorption after dental trauma: a systematic scoping review. BMC Oral Health. 2021;21(1):1–14. https://doi.org/10.1186/s12903-021-01510-6
53. Shah DJS, Mathumathi DA. A Clinico-Radiographic (2D&3D) Analysis of Ameloblastoma: With Impacted and Non-Impacted Teeth. Sch J Dent Sci. 2021;8(9):276–83.
54. Abdalla-Aslan R, Friedlander-Barenboim S, Aframian DJ, Maly A, Nadler C. Ameloblastoma incidentally detected in cone-beam computed tomography sialography: A case report and review of the literature. J Am Dent Assoc. 2018;149(12):1073–80. https://doi.org/10.1016/j.adaj.2018.09.003
55. Miranda-Viana M, Madlum DV, Oliveira-Santos N, Gaêta-Araujo H, Haiter-Neto F, Oliveira ML. Influence of the image file format of digital periapical radiographs on the diagnosis of external and internal root resorptions. Clin Oral Investig. 2021;25(8):4941–8.
56. Taravati S, Balak Z, Rakhshan V. Diagnostic accuracy of periapical radiography in detection and measurement of the external root resorption in primary molars: a single-blind prospective clinical study. Int J Dent. 2022;2022:7031086. doi:10.1155/2022/7031086
Downloads
Published
Issue
Section
Citation Check
License
Copyright (c) 2026 Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI)

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.










































